Anticonvulsant activity of bioflavonoid gossypin
نویسندگان
چکیده
منابع مشابه
Concomitant Supplementation of Gossypin: a Bioflavonoid Protects Lead and Ethanol Induced Oxidative Stress in Rats
The objective of the present study was to evaluate the protective efficacy of gossypin coadministration during lead-ethanol co-exposure. In one of our earlier study we reported the protective efficacy of gossypin against lead induced oxidative stress and it was of interest to observe the efficacy in the situation of combined lead-ethanol exposure. Animals were exposed to lead as lead nitrate (2...
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The anticonvulsant activity of Astragalus squarrosus total extract was assessed in pentylenetetrazole (PTZ)-induced convulsion in mice, with diazepam as the standard drug, while mechanistic studies were also conducted using flumazenil, a GABA A-benzodiazepine receptor complex site antagonist. The extract produced protection against convulsion at 400 mg/kg, comparable with protection of...
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Objective: Annona senegalenesis Pers is a sprawling shrub belonging to the family Annonaceae, and is mainly used in ethnomedicine. The use of decoction of A. senegalenesis is very prominent in the management of various conditions ranging from bacterial infection, worm infestation, snake bites, pyrexia and febrile convulsion in folk medicine. Methods: The investigation on anti...
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Objective: Annona senegalenesis Pers is a sprawling shrub belonging to the family Annonaceae, and is mainly used in ethnomedicine. The use of decoction of A. senegalenesis is very prominent in the management of various conditions ranging from bacterial infection, worm infestation, snake bites, pyrexia and febrile convulsion in folk medicine. Methods: The investigation on anti...
متن کاملNaringenin: a weakly estrogenic bioflavonoid that exhibits antiestrogenic activity.
Treatment of immature 21-day-old female Sprague-Dawley rats with 17 beta-estradiol (E2) (0.5 microgram/rat) caused a significant increase in uterine wet weight, DNA synthesis, progesterone receptor (PR) binding, and peroxidase activity. At doses as high as 40 mg/rat, the bioflavonoid naringenin did not cause a significant increase in any of these E2-induced responses. However, in rats cotreated...
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ژورنال
عنوان ژورنال: Bangladesh Journal of Pharmacology
سال: 2008
ISSN: 1991-0088,1991-007X
DOI: 10.3329/bjp.v4i1.1081